Research work

Department staff are involved in the implementation of scientific and technical projects

2015-2018

International grant “Creation of the German-Kazakhstani system for the diagnosis of infectious diseases caused by potential biological agents”.

Source of funding: Bundeswehr Institute of Microbiology, Germany.

Program Leader: Sandra Essbauer

Responsible performer: Yegemberdieyva R.A.

Deadlines: 2014-2016

Scientific and technical program “Population study of the polymorphism

of the gene IL 28B by viral hepatitis C in the Republic of Kazakhstan”.

Source of funding: MES RK

Leader: Shopaeva GA

Deadlines: 2015-2017

WHO short-term educational grant “Implementation of the scientific

training on the model of echinococcosis in Kazakhstan.”

Source of funding: WHO

Responsible performer: Duysenova A.K.

Deadlines: 2016

Intra-university grant “Clinical-epidemiological and medico-social

monitoring of actual parasitic invasions among students (enterobiosis, hymenolepidosis, ascariasis, echinococcosis, opisthorchiasis, teneyarinhosis, toxocarosis).”

Source of funding: S.D. AsfendiyarovKazNMU

Leader: Bayekeeva K.T.

Deadlines: 2016

International grant “German-Kazakhstani cooperation in the field of

bioprotection and biosafety”.

Source of funding: Bundeswehr Institute for Microbiology, Germany.

Program Leader: Sandra Essbauer

Responsible performer: Yegemberdiyeva R.A.

Deadlines: 2017–2019

“Multicenter international prospective study of the characteristics of

pneumococcal infection”

Source of funding: Rostropovich-Vishnevskaya Foundation

Scientific advisor: prof. Ramazanova B.A.

Performer: A.K. Duysenova

Deadlines: 2017–2018

“Study of the types and genotypes of rickettsia circulating in the natural

foci of the southern region of Kazakhstan.”

Source of funding: MES RK

Co-Head: A.M. Dmitrovsky

Deadlines: 2018-2020.

” Study of the distribution of different virus genotypesand the risk factors

of West Nile fever in Kazakhstan.”

Source of funding: MES RK

Co-Head: R. Yegemberdiyeva

Deadlines: 2018-2020.

The Department of Infectious and Tropical Diseases organized and held a number of Republican conferences with international participation

on infectious diseases.

2015-2019

Republican scientific-practical conference with international participation

“Infectious diseases: diagnosis, treatment and prevention at the primary health care”, dedicated to the 80th anniversary of the department of infectious and tropical diseases and the 85th anniversary of KazNMU, Almaty, 17-18.11.15. Visiting professors of KazNMU took part in the conference:

– Prof. Kozlov S.S., Head of the Parasitology Course of the Military Medical Academy named after S.M. Kirov, Ministry of Defense of the Russian Federation

– Prof. N. Rudakov, Director of the Omsk Research Institute of Natural Foci Infections, Head of the Department of Microbiology, Virology and Immunology, Omsk Medical Academy, Ministry of Health of Russia.

Head of Department prof. Duisenova A.K. delivers a lecture on the history

of Department infectious diseases

Scientific-practical seminar in the online mode with the University of Pavia (Italy) “Diagnosis of echinococcosis in Kazakhstan: experience and prospects”, Almaty, 01.15.2016

3Scientific and practical seminars in the framework of an educational grant to strengthen research capacity and knowledge management for the project “Implementation of the scientific training on the model of echinococcosis in Kazakhstan.”(WHO, Center for the Study of Tropical Diseases): 20.04-25.04.2016, 31.10 .2016- 4.11.2016, 07.07.2016-07.07.2016.

International trainers:

Enrico Brunetti, MD, Associate Professor of the Department of Infectious Diseases, University of Pavia, full-time doctor of the Department of Infectious and Tropical Diseases, San Matteo Hospital, and co-director of the Center, working with WHO on the clinical management of cystic echinococcosis, Pavia, Italy;

Mara Mariconti, PhD, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia; Fellow of the Center, collaborating with WHO on clinical management of cystic echinococcosis, Pavia, Italy.

Results of the educational grant:

– A multidisciplinary team of specialists in the field of diagnosis and treatment of cystic liver echinococcosis has been chtatedin the Republic of Kazakhstan;

Master-class of Enrico Brunetti

– Conclusion of the Memorandum between KazNMU named after S.D.Asfendiyarov and the University of Pavia (Pavia, Italy);

– Development and implementation of the Clinical Protocol “Cyst echinococcosis of the liver in adults”, approved by the RCHD Expert Council in 2016

– PhD candidate MustapaevaAigerimare doing PhD on the topic “Improving the ultrasound diagnosis of cystic echinococcosis of the liver”, the specialty “Medicine”, deadlines 2016-2018.

Responsible performer is Head of the Department, Professor Duisenova A.K., performer – Associate Professor Bayekeeva K.T.

There are Participants of the educational grant workshop to strengthen research capacity and knowledge management for the project “Implemention of the scientific training on the model of Echinococcus in Kazakhstan” (WHO, Center for the Study of Tropical Diseases).

International Scientific and Practical Conference dedicated to the Days of the S.D. AsfendiyarovKazNMU “School of General Practitioner”, Almaty, May 16, 2017

DuffneMoffet is Director of the Central Asian CDC Office (Atlanta, USA) and Department staff at the International Conference “School of General Practitioner”

Presentation of the head of the department prof. Duysenova A.K. at the conference

A master class “Development and implementation of an action algorithm for identifying a patient with a particularly dangerous infectious disease: the experience of the Universiade -2017”was heid at the conference.

Demonstration of modern anti-plague costumes

Department staff made oral and poster presentations on the topic “Standard definition of a case of a highly dangerous infection based on the results of their own clinical observations:

Dmitrovsky A.M., Duysenova A.K. “Fundamentals of biosafety and bioprotection. Algorithms of action in identifying a patient with a particularly dangerous infectious disease (oral)

Yegemberdiyeva R.A. “Hemorrhagic fevers: Ebola virus disease, CCHF” (oral)

3.Dmitrovsky A.M., Duysenova A.K., Yegemberdiyeva R.A., Shokalakova A.K. “Confirmed case of tularemia ” (poster)

Duysenova A.K., Seydulaeva L.B., Kashim J.K. “Probable case of

anthrax” (poster)

Yegemberdiyeva R.A., Dmitrovsky A.M., Baykhozhaeva R.Zh. “Presumptive case of Ebola fever” (poster)

Dmitrovsky A.M., Duysenova A.K., Umeshova L.A. “Anthrax in Kazakhstan. Situation 2016 “(poster)

Sadykova A.M., Shopaeva G.A., Konysova A.K., Sarsenbiyeva A.A. “Imported case of cholera in Almaty” (poster)

Ospanbekova N.K. “Differential diagnosis of botulism at the level of primary health care” (poster)

Seydulaeva L.B., Bayekeeva K.T., Duysenova A.K., Yegemberdiyeva R.A. “Imported tropical diseases in general medical practice” (poster)

Dmitrovsky A.M., Yegemberdiyeva R.A., Shokalakova A.K. “On the standard definition of case of tularemia” (poster)

Ospanbekova N.K. “Clinical manifestations of Klebsiella in general

medical practice” (poster)

Department staff with poster presentations

International Scientific and Practical Conference “Global security threats, a range of epidemic and pandemic risks”, Almaty, April 16, 2018 with the participation of international trainers: 1. Prof. Christopher H. Logue, Department of Health, England, Course on training in the fight against new and dangerous pathogens; 2. Dr. Ingmar Jansen, National Institute of Public Health and the Environment (RIVM), The Netherlands

PresentationofIngmarJansen.

Discussion of conference participants

Republican seminar “Actual issues of parasitic and

vector-borne diseases ”, Almaty, May 30-31, 2019 with the participation of prof. Rudakova N.V., Director of the Omsk Research Institute of Natural Focal Infections, Head of the Department of Microbiology, Virology and Immunology, Omsk Medical Academy, Ministry of Health of Russia.

Speech by prof. Rudakova N.V. with the report “Modern views on rickettsioses in Russia

International conference “Flu and SARS: current trends

in diagnostics, treatment and prevention ”, dedicated to“ University Days – 2019 ”, Almaty, 12/04/2019

Iskakova Aiman Kadyrhanovna, Leader in the implementation of BMJ in Kazakhstan, project manager, doctor of medical sciences, Nur Sultan with a report “BMJ Project (British Medical Journal) in Kazakhstan: Clinical Decision Support Initiative. The use of BMJ resources in postgraduate and further education of the Republic of Kazakhstan ”

Scientific works of employees:

2015-2016

articles have published, 14 abstracts, including 4 abstracts – in English:

«MLVA genotyping of Brucellamelitensis in Kazakhstan» всборнике 15

medical biodefense conferenМюнхен, Германия. 2016. 26-29 апреля P.61-62. Syzdykov M. et.al.

«Tick-borne diseases in Kazakhstan» всборнике 14th International

Conference on Lyme borrelioses and other Tick-borne diseases. Vienna, Austria.27-30 september, 2015. P.58. Yegemberdiyeva R.

«Southern Kazakhstan as a melting pot for human pathogenic Rickettsiae» в сборнике 15 medical biodefense conferenМюнхен, Германия. 2016. 26-29 april P.29 Yegemberdiyeva R., Dmitrovsky A.

«The German Parthnership Program Supports Biorisk Management in

Kazakhstan» всборнике 15 medical biodefense conferenМюнхен, Германия. 2016. 26-29 april.- P.73/ Yegemberdiyeva R., Dmitrovsky A.

Presentation of prof. Yegemberdiyeva R.A. at a conference in Oslo (Norway), 30.05.2015

Participation of prof. Yegemberdiyeva R.A. at a conference in Munich, 26-29.04.2016г.

2016-2017

articles have published, 4 abstracts–in English:

«Spinal echenococcosis: A case report»// XXXI Internatuonal Congress of

the International Academy of Pathology. VirchowsArchiv European Journal of Pathology, 2016.- 469 (Suppl 1):S301- Duysenova A., Sapargaliyeva A., Pak D., Dostarbayev R.

«Clinical and Epidemiological TBE manifestation in Almaty

City»//(Espid 2017) 35th annual meeting of the european society for paediatric Infectious diseases 23/05/2017 – 27.05.2017- Madrid , Spain- Yegemberdiyeva R.A., Dmitrovskiy A.M.

«TBE in children in Kazakhstan»//(Espid 2017) 35th annual meeting of

theeuropean society for paediatric Infectious diseases 23/05/2017 – 27.05.2017- Madrid , Spain- Dmitrovskiy A.M., Yegemberdiyeva R.A., ShokalakovaА. K.

«Acute TBE case in the absence of IgM»»//(Espid 2017) 35th annual

meeting of the european society for paediatric Infectious diseases 23.05.2017 – 27.05.2017- Madrid, Spain- Dmitrovskiy A.M., Yegemberdiyeva R.A., Shokalakova А. K.

Presentation of prof. Dmitrovskiy A.M. and prof. Yegemberdiyeva R.A. at a

(ESPID 2017) 35th annual meeting of the European society for paediatric Infectious diseases 23- 27 May,2017- Madrid, Spain.

2017-2018

28 articles have published, including 1 article was been in the journal with impact factor: «The burden and epidemiology of community-acquired central nervous system infections: a multinational study»//Eur J ClinMicrobiol Infect Dis (2017) 36:1595-1611//Duissenova A., Shopаeva G.

10 abstracts, including 6 abstracts – in English:

«Tick-borne encephalitis in the Soutern part of Kazakhstan»//22nd

International scientific Conference “Current Issues on Zoonotic Diseases” 05.07.2017. Volume 22, Ulaanbaatar, P. 7-13., Dmitrovskiy A.M., Yegemberdiyeva R.A., Abdiyeva K., Turebekov N.

«Almaty region as a melting pot for the new tick-borne rickettsiae species

in Kazakhstan»//22nd International scientific Conference “Current Issues on Zoonotic Diseases” 05.07.2017. Volume 22, Ulaanbaatar, P. 59-64. Yegemberdiyeva R.A., Dmitrovskiy A.M., Turebekov N., Abdiyeva K.

«Клинические особенности сальмонеллезов, вызванные

сальмонеллами редких групп»// WorldScience/ №4 (32) Vol.4, April, 2018.- С.34-37. СадыковаА.М., ЕргалиеваА.А.

The problems of TBE diagnostics in children in Kazakhstan//10th World

Congress of the World Society for Pediatric Infectious Diseases г.Шенчжень (Китай) 04.12.-06.12.2017.Dmitrovskiy A.M., Yegemberdiyeva R.A.

TBE case definition evaluation in Kazakhstan// 10th World Congress of

the World Society for Pediatric Infectious Diseases г.Шенчжень (Китай) 04.12.. Dmitrovskiy A.M., Yegemberdiyeva R.A.

TBE diagnostics and surveillance problems in Kazakhstan//10th World

Congress of the World Society for Pediatric Infectious Diseases г.Шенчжень (Китай) 04.12. Dmitrovskiy A.M., Yegemberdiyeva R.A.

2018-2019

7 articles have published, including 2 article was been in the journal with impact factor:

«Seroepidemioligical and molecular investigations of infections with Crimean-Congo hemorrhagic fever virus in Kazakhstan »// International Journal of Infectious Diseases 78 (2019) 121-127// Dmitrovskiy A., Yegemberdiyeva R.

«Prevalence of Rickettsia species in ticks including identification of unknown species in two regions in Kazakhstan»// Parasites & Vectors (2019) 12:197, 3-16

// Dmitrovskiy A., Yegemberdiyeva R.

12 abstracts, including 8 abstracts – in English:

Epidemiological characteristics in the southern regions of Kazakhstan//29th ECCMID, Amsterdam, Netherlands, 13-16 April,2019// Mustapayeva A., Duisenova A., Zholdybay Zh., Iskakova F.

Orthohantavirus infections as a cause of fever of unknown origin in Kazakhstan//16-th Medical Biodefense Conference, Munich, 28-31 October, 2018, P.43-44// Tukhanova N., Shin A., Abdiyeva K., Turebekov N., Yegemberdiyeva R.

First molecular biological analysis of tick-borne encephalitis virus in Akmola Oblast and East-Kazakhstan Oblast//16-th Medical Biodefense Conference, Munich, 28-31 October, 2018, P.100-101// Shin A., Tukhanova N., Abdiyeva K., Turebekov N., Yegemberdiyeva R.

Prevalence of Rickettsia species in ticks in Kazakhstan//16-th Medical Biodefense Conference, Munich, 28-31 October, 2018, P. 101// Turebekov N., K., Yegemberdiyeva R., Dmitrovskiy A. and all.

Seroepidemioligical and molecular investigations of subclinical infections with Crimean-Congo hemorrhagic fever virus in Kazakhstan//16-th Medical Biodefense Conference, Munich, 28-31 October, 2018, P. 101// Abdiyeva K., Turebekov N., Tukhanova N., Dmitrovskiy A., Yegemberdiyeva R.

The epidemiological influence of tick-borne encephalitis in the southern part in Kazakhstan// 16-th Medical Biodefense Conference, Munich, 28-31 October, 2018, P. 102.//Abdiyeva K., Turebekov N., Dmitrovskiy A., Yegemberdiyeva R.

Kazakhstans experience of BS&S specialists training in the framework of EU CBRN CoE Project 53: Strengtening the national legal framework and provision of specialized training on biosafety and biosecurity in Central Asian countries//16-th Medical Biodefense Conference, Munich, 28-31 October, 2018, P. 107-108.// Dmitrovskiy A., Yeraliyeva L., Yegemberdiyeva R.

Investigation of tick-borne encephalitis spread in the non-endemic regions of Kazakhstan//16-th Medical Biodefense Conference, Munich, 28-31 October, 2018, P. 117-118.// Yegemberdiyeva R., Dmitrovskiy A., Oradova A.